Laboratory of yeast functional genomics

Heads: Prof. Lubomir Tomaska (tomaska@fns.uniba.sk) / Prof. Jozef Nosek (nosek@fns.uniba.sk)

Address: Departments of Genetics and Biochemistry, Comenius University, Faculty of Natural Sciences, Mlynska dolina, 842 15 Bratislava, Slovakia

Tel: +421-2-60296-433, +421-2-60296-507, +421-2-60296-536

Fax: +421-2-60296-452, +421-2-60296-434

Research topics:

The work in the laboratory is aimed at description and understanding of:

• Mechanisms of maintenance of the ends of linear DNA molecules (telomeres) including the modes of their stabilization, replication, dynamics
• Evolutionary trajectories leading to contemporary linear genophores
• Mechanisms of replication, stabilization and inheritance of mitochondrial genomes

• Structure and dynamics of mitochondrial chromosomes/nucleoids

• Molecular taxonomy based on comparative genomics of mitochondrial genomes
• Biogenesis of the organelles of eukaryotic cells, especially mechanisms of morphogenesis and inheritance of mitochondria and their relationships to ion homeostasis
• Regulation of dimorphic transition between yeast and hyphae forms of pathogenic fungi

Link: http://monet.fns.uniba.sk/kbi/kovlab/