Laboratory of Neurophysiology

The Laboratory of Neurophysiology (Faculty of Medicine - ULB) deals with the study of the nervous system physiology and physiopathology through an integrated approach allowing to go from the gene to the functions that it determines and from the individual synapse to the neuronal network. This approach combines the characterization of specific genes and the study of their functions by their invalidation or surexpression in animal models, the study of chemical neuromessengers functions and their interactions by using morphological techniques of functional neuroanatomy, the study of the modulation and plasticity of the neuronal excitability and synaptic transmission by using electrophysiological approaches and theoretical simulation, and behavioral analysis. In this line, five topics have been developed and are centered on: 1. the physiology of the basal ganglia system. 2. the cerebellar physiology. 3. the neurobiology of adult stem cells, from neural and mesenchymal origin 4. the enteric nervous system and interstitial cells of Cajal. 5. the dorsal horn of spinal cord.